Effect Extract And Nanoparticles of Ginger Root on Pseudomonas Bacteria That Isolation From Otitis Infection

Abstract

 This study was conducted to test the inhibitory activity of alcoholic extracts (using ethanol) of ginger roots, as well as the inhibitory activity of alcoholic and aqueous  nanoparticles of ginger roots against (Pseudomonas bacteria) , isolated from cases of  ear infection , the natural effective antibacterial chemical compounds contained in the prepared nanoparticles were detected. 100 samples were collected from the patients and patients in Alexandria General Hospital and Morgan Teaching Hospital from October /2022 to April /2023 and included isolates for patient of different ages and genders. The number of bacterial isolates that came from females was 42 and the number of isolates from males was 58. The bacterial isolates calculator tested the directions of 8 antibiotics circulating in health institution. The sensitivity and resistant varied according to nature of the antibiotic and the type of bacterial isolate tested Pseudomonas  bacteria, it showed sensitivity against the antibiotic Imipenem, but it had high resistance against the antibiotic Gentamycin. The alcoholic extracts as well as the alcoholic nanoparticles of ginger roots ,showed an effective  inhibitory effect on the bacterial isolates , and the nature of the extract and that  the inhibitory effectiveness is directly proportional to the increase in concentration , so at a effectiveness of 40 of the extract, the effectiveness was better than the effectiveness of the extract at a concentration of 10  , therefore , the inhibitory activity of  alcoholic nanoparticles of ginger root  was directly proportional to the increase in concentration , as it was higher at concentration 500 , but at concentration 100 the inhibition was lees than that.