Evaluation of Animal and Plant Milks Against High-Fat Diet-Induced Hypercholesterolemia and Liver Dysfunction in Rats

Authors
  • Sura Maamoon Al-Zubaidi1, Mohammed Ahmad Jassim2

    Author

Abstract
To compare the effects of cow's milk, on some metabolic and biochemical parameters of rats submitted to hypercholesterolemic diet. Hypercholesterolemia was experimentally induced in rats. Liver function enzymes and blood glucose levels were also monitored to assess the effects of the different milk types on body weight and lipid profile. The hypercholesterolemic control group showed a marked deterioration in the parameters measured; it included increased body weight, total cholesterol, triglycerides, low-density lipoprotein (LDL) cholesterol, liver enzyme activities (ALT, AST, and ALP), and blood glucose concentration when compared with the healthy control group. All milk-treated groups showed significant improvements in these indicators. Oat milk showed the best results in all beneficial effects from all treatments tested, with the highest reductions in body weights and most pronounced improvements in lipid profile, liver enzyme activities, and blood glucose levels. Soy milk, almond milk, and cow's milk also showed favorable effects, though to a lesser degree than oat milk. The results generally show that the types of milk tested could be useful functional foods in managing metabolic disorders related to hypercholesterolemia, and in improving general health. Oat milk, in particular, falls into this category.
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Published
2026-09-30
Section
Articles

How to Cite

Evaluation of Animal and Plant Milks Against High-Fat Diet-Induced Hypercholesterolemia and Liver Dysfunction in Rats. (2026). Euphrates Journal of Agricultural Science, 18(3). https://ejs-agri.com/index.php/EJAS/article/view/355